20260420_Epithalon_10MG.png
20260420_Epithalon_10MG.png

Epithalon

$49.99

Full Name: Epithalon (Epitalon, Epithalone)

CAS Number: 307297-39-8

Molecular Formula: C₁₄H₂₂N₄O₉

Molecular Weight: 390.35 g/mol

Amino Acid Sequence: Ala-Glu-Asp-Gly

Appearance: White lyophilized powder

Solubility: Water-soluble

Storage: -20°C, desiccated, protected from light

Full Name: Epithalon (Epitalon, Epithalone)

CAS Number: 307297-39-8

Molecular Formula: C₁₄H₂₂N₄O₉

Molecular Weight: 390.35 g/mol

Amino Acid Sequence: Ala-Glu-Asp-Gly

Appearance: White lyophilized powder

Solubility: Water-soluble

Storage: -20°C, desiccated, protected from light

Research Context

Epithalon is a synthetic tetrapeptide based on the natural peptide epithalamin, isolated from the pineal gland by Professor Vladimir Khavinson at the Saint Petersburg Institute of Bioregulation and Gerontology. It is the most well-known member of the Khavinson bioregulator peptide family.

Research interest centers on telomerase activity modulation — epithalon was one of the first short peptides reported to activate telomerase expression in human somatic cells (Khavinson et al., 2003). This finding positioned it as a tool compound for researchers studying telomere biology, cellular senescence, and the bioregulator peptide hypothesis.

Key References

  1. Khavinson VK, et al. (2003). "Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells." Bull Exp Biol Med. 135(6):590-592. PMID: 12937682

  2. Anisimov VN, et al. (2001). "Effect of epithalon on biomarkers of aging." Bull Exp Biol Med. 132(1):716-722.