20260420_Ipamorelin_5MG.png
20260420_Ipamorelin_5MG.png

Ipamorelin

$65.00

Full Name: Ipamorelin (Aib-His-D-2-Nal-D-Phe-Lys-NH₂)

CAS Number: 170851-70-4

Molecular Formula: C₃₈H₄₉N₉O₅

Molecular Weight: 711.85 g/mol

PubChem CID: 9831659

Appearance: White lyophilized powder

Solubility: Water-soluble

Storage: -20°C, desiccated, protected from light

Full Name: Ipamorelin (Aib-His-D-2-Nal-D-Phe-Lys-NH₂)

CAS Number: 170851-70-4

Molecular Formula: C₃₈H₄₉N₉O₅

Molecular Weight: 711.85 g/mol

PubChem CID: 9831659

Appearance: White lyophilized powder

Solubility: Water-soluble

Storage: -20°C, desiccated, protected from light

Research Context

Ipamorelin is a synthetic pentapeptide growth hormone secretagogue developed by Novo Nordisk in the late 1990s. It selectively activates the ghrelin/GHSR receptor without significantly affecting cortisol or prolactin levels in preclinical models — a selectivity profile that distinguishes it from earlier secretagogues like GHRP-6 and GHRP-2.

Published research examines receptor binding selectivity, structure-activity relationships in growth hormone secretagogue design, and comparative pharmacology with other secretagogue classes. Ipamorelin's well-characterized selectivity profile makes it a valuable reference compound for researchers studying GHSR signaling specificity.

Key References

  1. Raun K, et al. (1998). "Ipamorelin, the first selective growth hormone secretagogue." Eur J Endocrinol. 139(5):552-561. PMID: 9849822

  2. Anderson LL, et al. (2001). "Ipamorelin increases bone mineral content." J Endocrinol. 171(1):55-62. PMID: 11572790

  3. Jimenez-Reina L, et al. (2002). "Structure-activity relationships of growth hormone secretagogues." Neuroendocrinology. 75(5):286-296.