NAD+

$63.99

Full Name: β-Nicotinamide Adenine Dinucleotide, oxidized form

CAS Number: 53-84-9

Molecular Formula: C₂₁H₂₇N₇O₁₄P₂

Molecular Weight: 663.43 g/mol

PubChem CID: 5893

Appearance: White to yellowish lyophilized powder

Solubility: Water-soluble

Storage: -20°C, desiccated, protected from light and moisture

Full Name: β-Nicotinamide Adenine Dinucleotide, oxidized form

CAS Number: 53-84-9

Molecular Formula: C₂₁H₂₇N₇O₁₄P₂

Molecular Weight: 663.43 g/mol

PubChem CID: 5893

Appearance: White to yellowish lyophilized powder

Solubility: Water-soluble

Storage: -20°C, desiccated, protected from light and moisture

Research Context

NAD+ is a coenzyme found in all living cells that plays a central role in cellular metabolism, serving as an electron carrier in redox reactions and as a substrate for enzymes including sirtuins and poly(ADP-ribose) polymerases (PARPs). It is one of the most fundamental molecules in biochemistry, with over 50,000 PubMed-indexed articles.

As a reference standard, NAD+ is widely used in enzymatic assay development, sirtuin activity studies, and metabolic pathway characterization. It is also the subject of extensive research in cellular aging and metabolic regulation.

Key References

  1. Verdin E. (2015). "NAD⁺ in aging, metabolism, and neurodegeneration." Science. 350(6265):1208-1213. PMID: 26785480

  2. Imai S, Guarente L. (2014). "NAD+ and sirtuins in aging and disease." Trends Cell Biol. 24(8):464-471. PMID: 24786309

  3. Yoshino J, et al. (2018). "NAD⁺ intermediates: the biology and therapeutic potential." Cell Metab. 27(3):513-528. PMID: 29249689