Tesamorelin

$50.00

Full Name: Tesamorelin acetate (trans-3-hexenoic acid-GHRH(1-44))

CAS Number: 218949-48-5

Molecular Formula: C₂₂₁H₃₆₆N₇₂O₆₇S₁

Molecular Weight: 5,136 g/mol

Appearance: White lyophilized powder

Solubility: Water-soluble

Storage: -20°C, desiccated, protected from light

Full Name: Tesamorelin acetate (trans-3-hexenoic acid-GHRH(1-44))

CAS Number: 218949-48-5

Molecular Formula: C₂₂₁H₃₆₆N₇₂O₆₇S₁

Molecular Weight: 5,136 g/mol

Appearance: White lyophilized powder

Solubility: Water-soluble

Storage: -20°C, desiccated, protected from light

Research Context

Tesamorelin is a synthetic analog of human GHRH(1-44) with a trans-3-hexenoic acid modification at the N-terminus, developed by Theratechnologies. It is one of the few peptides in the research catalog that has received FDA approval (under the brand name Egrifta, 2010) for a specific indication, providing researchers with the advantage of extensive published human pharmacokinetic and safety data.

The compound is valuable as a reference standard for GHRH receptor pharmacology, comparative peptide modification studies, and as a well-characterized control compound for HPLC and mass spectrometry method validation.

Key References

  1. Falutz J, et al. (2007). "Metabolic effects of a growth hormone-releasing factor in patients with HIV." N Engl J Med. 357(23):2359-2370. PMID: 18057338

  2. Stanley TL, et al. (2014). "Effects of tesamorelin on inflammatory and cardiovascular biomarkers." JAIDS. 66(1):39-45. PMID: 24457631